Gene
rargb
- ID
- ZDB-GENE-070314-1
- Name
- retinoic acid receptor, gamma b
- Symbol
- rargb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Involved in determination of left/right symmetry; intrahepatic bile duct development; and negative regulation of BMP signaling pathway. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in several structures, including blastoderm; head; neural crest; pectoral fin; and tail bud. Orthologous to human RARG (retinoic acid receptor gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017621 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Garnaas et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Domain | IPR047158 | Retinoic acid receptor, ligand-binding domain |
| Domain | IPR047159 | Retinoic acid receptor, DNA-binding domain |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003078 | Retinoic acid receptor |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Retinoic acid receptor | Retinoic acid receptor, DNA-binding domain | Retinoic acid receptor, ligand-binding domain | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A2T928
|
489 |
Interactions and Pathways
No data available
Plasmids
No data available