Gene
zgc:158846
- ID
- ZDB-GENE-070209-50
- Name
- zgc:158846
- Symbol
- zgc:158846 Nomenclature History
- Previous Names
-
- krtt2c6 (1)
- wu:fb58f07
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in autosomal dominant woolly hair; ectodermal dysplasia 7; hypotrichosis 13; hypotrichosis 3; and liver cirrhosis. Orthologous to several human genes including KRT8 (keratin 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Cuevas et al., 2023
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intermediate filament protein, conserved site | Intermediate filament, rod domain | Keratin, type II | Keratin type II head |
|---|---|---|---|---|---|
|
UniProtKB:A2RV44
|
486 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:158846-201
(1)
|
Ensembl | 1,917 nt |
Interactions and Pathways
No data available
Plasmids
No data available