Gene
kdm4c
- ID
- ZDB-GENE-070209-38
- Name
- lysine (K)-specific demethylase 4C
- Symbol
- kdm4c Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable histone H3K36 demethylase activity and histone H3K9 demethylase activity. Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Is expressed in female organism. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pan et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR002999 | Tudor domain |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR003349 | JmjN domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR034732 | Extended PHD (ePHD) domain |
| Domain | IPR040477 | Lysine-specific demethylase 4-like, Tudor domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | Extended PHD (ePHD) domain | JmjC domain | JmjN domain | Lysine-specific demethylase 4-like, Tudor domain | Tudor domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A2RRT0
|
1482 |
Interactions and Pathways
No data available
Plasmids
No data available