Gene
fosl2
- ID
- ZDB-GENE-070209-164
- Name
- FOS like 2, AP-1 transcription factor subunit
- Symbol
- fosl2 Nomenclature History
- Previous Names
-
- wu:fl03b09
- wu:fl17h04
- xx:fl17h04
- zgc:158347
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of cardiac muscle cell myoblast differentiation. Predicted to localize to nucleus. Is expressed in head; presumptive bulbus arteriosus; presumptive cardiac ventricle heart tube; and trunk. Orthologous to human FOSL2 (FOS like 2, AP-1 transcription factor subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Jahangiri et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Aplasia cutis-enamel dysplasia syndrome | 620789 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AP-1 transcription factor | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A2RUX8
|
341 | |||
|
UniProtKB:A0A8M2BKU3
|
302 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available