Gene
nrxn3a
- ID
- ZDB-GENE-070206-9
- Name
- neurexin 3a
- Symbol
- nrxn3a Nomenclature History
- Previous Names
-
- nrxn3aa
- nrxn3ab
- im:7144250
- wu:fj54c11
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to act upstream of or within angiogenesis and cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3).
- Genome Resources
- Note
-
nrxn3a has two isoforms, alpha (2 forms DQ641432 and DQ641433) and beta (DQ641434)
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144250 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR027789 | Syndecan/Neurexin domain |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin G domain | Neurexin-related cell adhesion and synaptic protein | Neurexin/syndecan/glycophorin C | Syndecan/Neurexin domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PKU0 | InterPro | 1464 | ||||||
| UniProtKB:A0A8M9PEA6 | InterPro | 1681 | ||||||
| UniProtKB:A0A8M9P901 | InterPro | 464 | ||||||
| UniProtKB:A0A8M9PEB2 | InterPro | 1470 | ||||||
| UniProtKB:A1XQY0 | InterPro | 672 | ||||||
| UniProtKB:A0A8M9P8Z3 | InterPro | 1686 | ||||||
| UniProtKB:A0A8M9P070 | InterPro | 1687 | ||||||
| UniProtKB:A0A8M9PNT7 | InterPro | 1673 | ||||||
| UniProtKB:A0A8M9P072 | InterPro | 1664 | ||||||
| UniProtKB:A1XQX8 | InterPro | 1697 | ||||||
| UniProtKB:A0A8M9PKT1 | InterPro | 1692 | ||||||
| UniProtKB:A0A8M9P074 | InterPro | 1462 | ||||||
| UniProtKB:A0A8M9P8Z6 | InterPro | 1473 | ||||||
| UniProtKB:A0A8M9PKT6 | InterPro | 1672 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
nrxn3a-204
(1)
|
Ensembl | 2,987 nt | ||
| mRNA |
nrxn3a-201
(1)
|
Ensembl | 3,623 nt | ||
| mRNA |
nrxn3a-202
(1)
|
Ensembl | 2,099 nt | ||
| mRNA |
nrxn3a-203
(1)
|
Ensembl | 2,408 nt | ||
| mRNA |
nrxn3a-208
(1)
|
Ensembl | 4,008 nt | ||
| ncRNA |
nrxn3a-004
(1)
|
Ensembl | 788 nt | ||
| ncRNA |
nrxn3a-005
(1)
|
Ensembl | 776 nt | ||
| ncRNA |
nrxn3a-006
(1)
|
Ensembl | 437 nt |
Interactions and Pathways
No data available
Plasmids
No data available