Gene
ncaph
- ID
- ZDB-GENE-070112-652
- Name
- non-SMC condensin I complex, subunit H
- Symbol
- ncaph Nomenclature History
- Previous Names
-
- si:dkeyp-86b9.4
- zgc:158618
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity. Acts upstream of or within mitotic sister chromatid segregation. Predicted to be located in chromosome and cytoplasm. Predicted to be part of condensin complex. Is expressed in brain; ciliary marginal zone; optic cup; and spinal cord. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPH (non-SMC condensin I complex subunit H).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Seipold et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Seipold et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 23 | Alliance | ?Microcephaly 23, primary, autosomal recessive | 617985 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR022816 | Condensin complex subunit 2/barren |
Domain Details Per Protein
| Protein | Length | Condensin complex subunit 2/barren |
|---|---|---|
|
UniProtKB:A0A8M9PKI5
|
690 | |
|
UniProtKB:A1L231
|
690 |
Interactions and Pathways
No data available
Plasmids
No data available