Gene

cdt1

ID
ZDB-GENE-070111-1
Name
chromatin licensing and DNA replication factor 1
Symbol
cdt1 Nomenclature History
Previous Names
  • fc37h07
  • im:7158083 (1)
  • wu:fc37h07
  • wu:fi38h09 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA polymerase binding activity. Involved in mitotic cell cycle. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Is expressed in several structures, including immature eye; mesoderm; proliferative region; pronephric duct; and somite. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Meier-Gorlin syndrome 4 Alliance Meier-Gorlin syndrome 4 613804
Associated With cdt1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014939 CDT1 Geminin-binding domain-like
Domain IPR032054 DNA replication factor Cdt1, C-terminal
Family IPR045173 DNA replication factor Cdt1
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR038090 DNA replication factor Cdt1, C-terminal WH domain superfamily
Domain Details Per Protein
Protein Length CDT1 Geminin-binding domain-like DNA replication factor Cdt1 DNA replication factor Cdt1, C-terminal DNA replication factor Cdt1, C-terminal WH domain superfamily Winged helix DNA-binding domain superfamily
UniProtKB:A0A8M6YZJ1 628
UniProtKB:E7F2R5 678
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cdt1-201 (1) Ensembl 2,432 nt
mRNA cdt1-202 (1) Ensembl 1,379 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations