Gene
g6pc3
- ID
- ZDB-GENE-061215-19
- Name
- glucose-6-phosphatase catalytic subunit 3
- Symbol
- g6pc3 Nomenclature History
- Previous Names
-
- zgc:158425
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable glucose-6-phosphatase activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. Is expressed in ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in severe congenital neutropenia 4. Orthologous to human G6PC3 (glucose-6-phosphatase catalytic subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhang et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| severe congenital neutropenia 4 | Alliance | Dursun syndrome | 612541 |
| severe congenital neutropenia 4 | Alliance | Neutropenia, severe congenital 4, autosomal recessive | 612541 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glucose-6-phosphatase | Phosphatidic acid phosphatase type 2/haloperoxidase | Phosphatidic acid phosphatase type 2/haloperoxidase superfamily |
|---|---|---|---|---|
|
UniProtKB:A1A5Z0
|
339 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available