Gene
f2rl1.1
- ID
- ZDB-GENE-061215-140
- Name
- coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
- Symbol
- f2rl1.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Acts upstream of or within regulation of negative chemotaxis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in keratinocyte and thrombocyte. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Alsrhani et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Protease-activated receptor | Protease-activated receptor 2 |
|---|---|---|---|---|---|
|
UniProtKB:A1A5V5
|
380 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
f2rl1.1-201
(1)
|
Ensembl | 1,641 nt | ||
| mRNA |
f2rl1.1-202
(1)
|
Ensembl | 879 nt |
Interactions and Pathways
No data available
Plasmids
No data available