Gene
bcl11ba
- ID
- ZDB-GENE-061207-62
- Name
- BCL11 transcription factor B a
- Symbol
- bcl11ba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in thymus. Orthologous to human BCL11B (BAF chromatin remodeling complex subunit BCL11B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 49 | Alliance | Immunodeficiency 49, severe combined | 617237 |
| Intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities | 618092 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Developmental and Hematopoietic Transcription Factors | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:A0A2R8Q8A6
|
814 | |||
|
UniProtKB:A0A8M3AR85
|
813 | |||
|
UniProtKB:X1WBZ3
|
776 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bcl11ba-202
(1)
|
Ensembl | 1,065 nt | ||
| mRNA |
bcl11ba-203
(1)
|
Ensembl | 3,240 nt | ||
| mRNA |
bcl11ba-204
(1)
|
Ensembl | 6,099 nt | ||
| mRNA |
bcl11ba-205
(1)
|
Ensembl | 8,016 nt | ||
| ncRNA |
bcl11ba-003
(1)
|
Ensembl | 543 nt |
Interactions and Pathways
No data available
Plasmids
No data available