Gene

erbin

ID

ZDB-GENE-061103-403

Name

erbb2 interacting protein

Symbol

erbin Nomenclature History

Previous Names

erbb2ip (1)
zgc:152984 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable ErbB-2 class receptor binding activity. Predicted to be involved in neurotransmitter receptor transport postsynaptic membrane to endosome and neurotransmitter receptor transport, endosome to postsynaptic membrane. Predicted to act upstream of or within negative regulation of NF-kappaB transcription factor activity and signal transduction. Predicted to be active in adherens junction and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Is expressed in intestine. Orthologous to human ERBIN (erbb2 interacting protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With erbin Human Ortholog

No data available

Associated With erbin Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Family	IPR050614	Synaptic Scaffolding LAP/MAGUK Families
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype	PDZ domain	PDZ superfamily	Synaptic Scaffolding LAP/MAGUK Families
UniProtKB:A0A8M2B2B1 InterPro	1359
UniProtKB:A0A8M2B233 InterPro	1392
UniProtKB:A0A0R4IEU0 InterPro	1330
UniProtKB:E7EYJ7 InterPro	1382

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	erbin-201 (1) Ensembl	Ensembl	4,165 nt	Select Tool ZFIN BLAST
mRNA	erbin-203 (1) Ensembl	Ensembl	4,916 nt	Select Tool ZFIN BLAST
mRNA	erbin-204 (1) Ensembl	Ensembl	4,714 nt	Select Tool ZFIN BLAST
mRNA	erbin-205 (1) Ensembl	Ensembl	7,498 nt	Select Tool ZFIN BLAST
mRNA	erbin-206 (1) Ensembl	Ensembl	3,751 nt	Select Tool ZFIN BLAST
mRNA	erbin-207 (1) Ensembl	Ensembl	2,201 nt	Select Tool ZFIN BLAST
ncRNA	erbb2ip-003 (1) Ensembl	Ensembl	679 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations