Gene

ppm1h

ID
ZDB-GENE-061027-190
Name
protein phosphatase, Mg2+/Mn2+ dependent, 1H
Symbol
ppm1h Nomenclature History
Previous Names
  • zgc:153678
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have [pyruvate dehydrogenase (lipoamide)] phosphatase activity and magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in positive regulation of pyruvate dehydrogenase activity. Predicted to localize to mitochondrion and nucleus. Is expressed in female organism. Orthologous to several human genes including PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1h Human Ortholog
No data available
Associated With ppm1h Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001932 PPM-type phosphatase-like domain
Family IPR015655 Protein phosphatase 2C
Homologous_superfamily IPR036457 PPM-type phosphatase-like domain superfamily
Domain Details Per Protein
Protein Length PPM-type phosphatase-like domain PPM-type phosphatase-like domain superfamily Protein phosphatase 2C
UniProtKB:Q05AL2 516
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ppm1h-201 (1) Ensembl 2,120 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations