Gene
nyx
- ID
- ZDB-GENE-061026-3
- Name
- nyctalopin
- Symbol
- nyx Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Involved in optokinetic behavior and visual perception. Used to study congenital stationary night blindness and congenital stationary night blindness 1A. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Is expressed in retinal ganglion cell layer; retinal inner nuclear layer; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human NYX (nyctalopin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Bahadori et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Peachey et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital stationary night blindness 1A | Alliance | Night blindness, congenital stationary (complete), 1A, X-linked | 310500 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| congenital stationary night blindness | WT + MO1-nyx | standard conditions | Bahadori et al., 2006 |
| congenital stationary night blindness 1A | WT + MO1-nyx | standard conditions | Peachey et al., 2012 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
|---|---|---|---|---|---|
|
UniProtKB:Q00P20
|
469 |
Interactions and Pathways
No data available
Plasmids
No data available