Gene

odad3

ID

ZDB-GENE-061013-787

Name

outer dynein arm docking complex subunit 3

Symbol

odad3 Nomenclature History

Previous Names

ccdc151
flanders
unm ts272
unm_ts272
zgc:152917

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Involved in axonemal dynein complex assembly; cilium movement; and determination of left/right symmetry. Acts upstream of or within several processes, including Kupffer's vesicle development; determination of left/right symmetry; and microtubule cytoskeleton organization. Located in ciliary basal body and motile cilium. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; intermediate mesoderm; nervous system; and pronephros. Used to study idiopathic scoliosis and primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 30. Orthologous to human ODAD3 (outer dynein arm docking complex subunit 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With odad3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary ciliary dyskinesia 30	Alliance	Ciliary dyskinesia, primary, 30	616037

Associated With odad3 Via Experimental Models

Human Disease	Fish	Conditions	Citations
idiopathic scoliosis	odad3^ts272/ts272	standard conditions	Rose et al., 2020
primary ciliary dyskinesia	odad3^ts272/ts272	standard conditions	Song et al., 2016