Gene

me1

ID
ZDB-GENE-061013-438
Name
malic enzyme 1, NADP(+)-dependent, cytosolic
Symbol
me1 Nomenclature History
Previous Names
  • zgc:153079
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to localize to mitochondrion. Orthologous to human ME1 (malic enzyme 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With me1 Human Ortholog
No data available
Associated With me1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015884 Malic enzyme, conserved site
Domain IPR012301 Malic enzyme, N-terminal domain
Domain IPR012302 Malic enzyme, NAD-binding
Family IPR001891 Malic oxidoreductase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Homologous_superfamily IPR037062 Malic enzyme, N-terminal domain superfamily
Homologous_superfamily IPR046346 Aminoacid dehydrogenase-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Aminoacid dehydrogenase-like, N-terminal domain superfamily Malic enzyme, conserved site Malic enzyme, NAD-binding Malic enzyme, N-terminal domain Malic enzyme, N-terminal domain superfamily Malic oxidoreductase NAD(P)-binding domain superfamily
UniProtKB:A7MC82 574
UniProtKB:A0A8M6Z1U3 544
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA me1-201 (1) Ensembl 1,956 nt
mRNA me1-202 (1) Ensembl 1,910 nt
mRNA me1-204 (1) Ensembl 2,054 nt
ncRNA me1-003 (1) Ensembl 782 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations