Gene
lpar6a
- ID
- ZDB-GENE-061013-343
- Name
- lysophosphatidic acid receptor 6a
- Symbol
- lpar6a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Enables lysophosphatidic acid receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Acts upstream of or within angiogenesis. Located in plasma membrane. Human ortholog(s) of this gene implicated in hypotrichosis 8. Orthologous to human LPAR6 (lysophosphatidic acid receptor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kalén et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypotrichosis 8 | Alliance | Hypotrichosis 8 | 278150 |
| hypotrichosis 8 | Alliance | Woolly hair, autosomal recessive 1, with or without hypotrichosis | 278150 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:Q08BG4
|
357 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lpar6a-201
(1)
|
Ensembl | 1,928 nt | ||
| mRNA |
lpar6a-202
(1)
|
Ensembl | 1,082 nt |
Interactions and Pathways
No data available
Plasmids
No data available