Gene
spint2
- ID
- ZDB-GENE-061013-323
- Name
- serine peptidase inhibitor, Kunitz type, 2
- Symbol
- spint2 Nomenclature History
- Previous Names
-
- fb52h04
- fe24a06
- wu:fb52h04
- wu:fe24a06
- zgc:153795
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 3. Is expressed in liver. Orthologous to human SPINT2 (serine peptidase inhibitor, Kunitz type 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 8 figures from Hatzold et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital secretory sodium diarrhea 3 | Alliance | Diarrhea 3, secretory sodium, congenital, syndromic | 270420 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Seven cysteines, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:F1QEV7
|
431 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spint2-201
(1)
|
Ensembl | 2,024 nt | ||
| mRNA |
spint2-202
(1)
|
Ensembl | 836 nt |
Interactions and Pathways
No data available
Plasmids
No data available