Gene
sfrp2
- ID
- ZDB-GENE-061013-293
- Name
- secreted frizzled-related protein 2
- Symbol
- sfrp2 Nomenclature History
- Previous Names
-
- hm:zeh0225
- sb:eu233
- zeh0225
- zgc:153618
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and non-canonical Wnt signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including adaxial cell; axis; musculature system; sensory system; and solid lens vesicle. Orthologous to human SFRP2 (secreted frizzled related protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu233 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhu et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001134 | Netrin domain |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041764 | SFRP2, cysteine-rich domain |
| Family | IPR015526 | Frizzled/secreted frizzled-related protein |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
| Protein | Length | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Netrin domain | Netrin module, non-TIMP type | SFRP2, cysteine-rich domain | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R238
|
294 |
Interactions and Pathways
No data available
Plasmids
No data available