Gene

tnfsf12

ID
ZDB-GENE-060929-376
Name
TNF superfamily member 12
Symbol
tnfsf12 Nomenclature History
Previous Names
  • TWEAK (1)
  • zgc:153941
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have tumor necrosis factor receptor binding activity. Predicted to be involved in immune response. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Is expressed in gill; heart; liver; and pleuroperitoneal region. Orthologous to several human genes including TNFSF12-TNFSF13 (TNFSF12-TNFSF13 readthrough).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnfsf12 Human Ortholog
No data available
Associated With tnfsf12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006052 Tumour necrosis factor domain
Family IPR051748 Tumor Necrosis Factor Ligand Superfamily
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Domain Details Per Protein
Protein Length Tumor Necrosis Factor Ligand Superfamily Tumour necrosis factor domain Tumour necrosis factor-like domain superfamily
UniProtKB:Q08BZ0 236
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tnfsf12-201 (1) Ensembl 2,172 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations