Gene
bmp7b
- ID
- ZDB-GENE-060929-328
- Name
- bone morphogenetic protein 7b
- Symbol
- bmp7b Nomenclature History
- Previous Names
-
- zgc:153025 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have BMP receptor binding activity and cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in prostate cancer. Is expressed in several structures, including digestive system; fin; neuroepithelial cell; optic cup; and sensory system. Orthologous to human BMP7 (bone morphogenetic protein 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Dong et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|
|
UniProtKB:Q08CJ5
|
427 | |||||
|
UniProtKB:F1QD07
|
427 |
Interactions and Pathways
Plasmids
No data available