Gene
rnf220a
- ID
- ZDB-GENE-060929-1006
- Name
- ring finger protein 220a
- Symbol
- rnf220a Nomenclature History
- Previous Names
-
- zgc:153254
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Involved in spinal cord patterning. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 23. Orthologous to human RNF220 (ring finger protein 220).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ma et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypomyelinating leukodystrophy 23 | Alliance | Leukodystrophy, hypomyelinating, 23, with ataxia, deafness, liver dysfunction, and dilated cardiomyopathy | 619688 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR031824 | E3 ubiquitin-protein ligase RNF220, middle domain |
| Domain | IPR040178 | E3 ubiquitin-protein ligase RNF220, RING finger |
| Family | IPR052443 | E3 ubiquitin-protein ligase RNF220-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase RNF220-like | E3 ubiquitin-protein ligase RNF220, middle domain | E3 ubiquitin-protein ligase RNF220, RING finger | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QNG6 | InterPro | 669 | |||||
| UniProtKB:A0A8M9PY31 | InterPro | 333 | |||||
| UniProtKB:A0A8M9Q9U5 | InterPro | 634 | |||||
| UniProtKB:A0A8M9PY03 | InterPro | 638 | |||||
| UniProtKB:A0A8M9QJR7 | InterPro | 660 | |||||
| UniProtKB:A0A8M9QJS5 | InterPro | 399 | |||||
| UniProtKB:A0A8M9QFI1 | InterPro | 577 | |||||
| UniProtKB:A0A8M9QFJ4 | InterPro | 307 | |||||
| UniProtKB:A0A8M9Q9V4 | InterPro | 364 | |||||
| UniProtKB:Q08CD0 | InterPro | 307 | |||||
| UniProtKB:A0A8M9PXZ7 | InterPro | 695 | |||||
| UniProtKB:A0A8M9QFH8 | InterPro | 615 | |||||
| UniProtKB:A0A8M9PY10 | InterPro | 603 | |||||
| UniProtKB:A0A8M9Q9V8 | InterPro | 338 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rnf220a-205
(1)
|
Ensembl | 855 nt | ||
| mRNA |
rnf220a-201
(1)
|
Ensembl | 1,614 nt | ||
| mRNA |
rnf220a-202
(1)
|
Ensembl | 1,734 nt | ||
| mRNA |
rnf220a-203
(1)
|
Ensembl | 762 nt | ||
| mRNA |
rnf220a-204
(1)
|
Ensembl | 694 nt | ||
| mRNA |
rnf220a-206
(1)
|
Ensembl | 604 nt | ||
| mRNA |
rnf220a-207
(1)
|
Ensembl | 1,339 nt | ||
| mRNA |
rnf220a-208
(1)
|
Ensembl | 2,707 nt | ||
| mRNA |
rnf220a-209
(1)
|
Ensembl | 5,466 nt |
Interactions and Pathways
No data available
Plasmids
No data available