Gene
fgf10b
- ID
- ZDB-GENE-060828-1
- Name
- fibroblast growth factor 10b
- Symbol
- fgf10b Nomenclature History
- Previous Names
-
- fgf25 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have fibroblast growth factor receptor binding activity and growth factor activity. Involved in animal organ development and ectodermal placode development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Is expressed in digestive system; lateral line system; mesoderm; pronephros; and tail bud. Orthologous to human FGF10 (fibroblast growth factor 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| aplasia of lacrimal and salivary glands | Alliance | Aplasia of lacrimal and salivary glands | 180920 |
| lacrimoauriculodentodigital syndrome 3 | Alliance | LADD syndrome 3 | 620193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:Q1XG75
|
187 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fgf10b-201
(1)
|
Ensembl | 1,739 nt | ||
| mRNA |
fgf10b-202
(1)
|
Ensembl | 564 nt |
Interactions and Pathways
No data available
Plasmids
No data available