Gene

hes2.2

ID
ZDB-GENE-060825-55
Name
hes family bHLH transcription factor 2, tandem duplicate 2
Symbol
hes2.2 Nomenclature History
Previous Names
  • Hes2b (1)
  • zgc:153398
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to localize to nucleus. Is expressed in eye; gill; heart; and liver. Orthologous to human HES2 (hes family bHLH transcription factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhou et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hes2.2 Human Ortholog
No data available
Associated With hes2.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR050370 Hairy and Enhancer of Split/HEY-related
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Hairy and Enhancer of Split/HEY-related Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:Q0P454 172
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hes2.2-201 (1) Ensembl 1,090 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations