Gene

rad54b

ID

ZDB-GENE-060810-50

Name

RAD54 homolog B

Symbol

rad54b Nomenclature History

Previous Names

im:7137737
im:7153525

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have DNA translocase activity. Predicted to be involved in double-strand break repair via homologous recombination and reciprocal meiotic recombination. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in colorectal cancer and non-Hodgkin lymphoma. Orthologous to human RAD54B (RAD54 homolog B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7137737 (1 image)
IMAGE:7153525 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rad54b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
colorectal cancer	Alliance	Colon cancer, somatic	114500
non-Hodgkin lymphoma	Alliance	Lymphoma, non-Hodgkin, somatic	605027

Associated With rad54b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000330	SNF2, N-terminal
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR049730	SNF2/RAD5-like, C-terminal helicase domain
Family	IPR050496	SNF2/RAD54 Helicase and DNA Repair
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR038718	SNF2-like, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Helicase, C-terminal domain-like	Helicase superfamily 1/2, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase	SNF2-like, N-terminal domain superfamily	SNF2, N-terminal	SNF2/RAD54 Helicase and DNA Repair	SNF2/RAD5-like, C-terminal helicase domain
UniProtKB:E9QHY4 InterPro	917

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rad54b-201 (1) Ensembl	Ensembl	3,229 nt	Select Tool
mRNA	rad54b-202 (1) Ensembl	Ensembl	1,926 nt	Select Tool ZFIN BLAST
mRNA	rad54b-203 (1) Ensembl	Ensembl	2,532 nt	Select Tool ZFIN BLAST
mRNA	rad54b-204 (1) Ensembl	Ensembl	2,571 nt	Select Tool ZFIN BLAST
mRNA	rad54b-205 (1) Ensembl	Ensembl	2,535 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations