Gene

wdr35

ID
ZDB-GENE-060810-148
Name
WD repeat domain 35
Symbol
wdr35 Nomenclature History
Previous Names
  • im:7159945 (1)
  • si:ch211-206k20.4
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Involved in cilium assembly. Predicted to localize to axoneme and intraciliary transport particle A. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; Sensenbrenner syndrome; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Stawicki et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wdr35 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cranioectodermal dysplasia 2 Alliance Cranioectodermal dysplasia 2 613610
short-rib thoracic dysplasia 7 with or without polydactyly Alliance Short-rib thoracic dysplasia 7 with or without polydactyly 614091
Associated With wdr35 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR024977 Anaphase-promoting complex subunit 4-like, WD40 domain
Family IPR017233 WD repeat protein 35
Family IPR039857 Intraflagellar transport protein 122/121 homolog
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Anaphase-promoting complex subunit 4-like, WD40 domain Intraflagellar transport protein 122/121 homolog WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily WD repeat protein 35
UniProtKB:A0A8M9Q9T9 1184
UniProtKB:B7ZD88 1203
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript wdr35-203 (1) Ensembl 800 nt
mRNA wdr35-201 (1) Ensembl 4,088 nt
ncRNA wdr35-003 (1) Ensembl 584 nt
ncRNA wdr35-004 (1) Ensembl 865 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations