Gene
lrata
- ID
- ZDB-GENE-060720-1
- Name
- lecithin retinol acyltransferase a
- Symbol
- lrata Nomenclature History
- Previous Names
-
- lrat
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylcholine-retinol O-acyltransferase activity. Predicted to be involved in retinol metabolic process and vitamin A metabolic process. Predicted to be located in membrane. Predicted to be active in rough endoplasmic reticulum. Is expressed in head; liver; pleuroperitoneal region; and visual system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Orthologous to human LRAT (lecithin retinol acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leber congenital amaurosis 14 | Alliance | Leber congenital amaurosis 14 | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinal dystrophy, early-onset severe | 613341 |
| Leber congenital amaurosis 14 | Alliance | Retinitis pigmentosa, juvenile | 613341 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Lecithin retinol acyltransferase | LRAT domain |
|---|---|---|---|
|
UniProtKB:Q6DC51
|
232 | ||
|
UniProtKB:F1Q7T8
|
225 |
Interactions and Pathways
No data available
Plasmids
No data available