Gene

ela3l

ID

ZDB-GENE-060710-2

Name

elastase 3 like

Symbol

ela3l Nomenclature History

Previous Names

ela2al
elaA (1)
elastaseA (1)
trypsin 5 (1)
wu:fd58f03
zgc:109943

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome. Is expressed in digestive system; exocrine pancreas; and pancreas. Orthologous to human CELA2A (chymotrypsin like elastase 2A) and CELA2B (chymotrypsin like elastase 2B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:109943 (2 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ela3l Human Ortholog

No data available

Associated With ela3l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018114	Serine proteases, trypsin family, histidine active site
Active_site	IPR033116	Serine proteases, trypsin family, serine active site
Domain	IPR001254	Serine proteases, trypsin domain
Family	IPR001314	Peptidase S1A, chymotrypsin family
Family	IPR050850	Peptidase S1 family, Elastase subfamily
Homologous_superfamily	IPR009003	Peptidase S1, PA clan
Homologous_superfamily	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold