Gene

otud7b

ID

ZDB-GENE-060616-1

Name

OTU deubiquitinase 7B

Symbol

otud7b Nomenclature History

Previous Names

za20d1 (1)
zgc:152772

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in Notch signaling pathway. Predicted to localize to cytoplasm and nucleus. Orthologous to human OTUD7B (OTU deubiquitinase 7B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158483 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With otud7b Human Ortholog

No data available

Associated With otud7b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002653	Zinc finger, A20-type
Domain	IPR003323	OTU domain
Domain	IPR054109	UBA-like domain
Family	IPR051346	OTU Domain-Containing Deubiquitinase

Domain Details Per Protein

Protein	Length	OTU domain	OTU Domain-Containing Deubiquitinase	UBA-like domain	Zinc finger, A20-type
UniProtKB:A0A8M2B4S2 InterPro	919
UniProtKB:A0JMB7 InterPro	917
UniProtKB:A0A8M2B591 InterPro	920
UniProtKB:A0A8M2B4T1 InterPro	918
UniProtKB:A0A8M9NZE1 InterPro	919