Gene

rasa4

ID
ZDB-GENE-060526-349
Name
RAS p21 protein activator 4
Symbol
rasa4 Nomenclature History
Previous Names
  • si:dkey-93f15.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity; metal ion binding activity; and phospholipid binding activity. Predicted to be involved in several processes, including cellular response to calcium ion; negative regulation of Ras protein signal transduction; and regulation of GTPase activity. Orthologous to human RASA4 (RAS p21 protein activator 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Gomez et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rasa4 Human Ortholog
No data available
Associated With rasa4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001562 Zinc finger, Btk motif
Conserved_site IPR023152 Ras GTPase-activating protein, conserved site
Domain IPR000008 C2 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR001936 Ras GTPase-activating domain
Domain IPR037777 RASA4, PH domain
Family IPR039360 Ras GTPase-activating protein
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily PH-like domain superfamily Pleckstrin homology domain RASA4, PH domain Ras GTPase-activating domain Ras GTPase-activating protein Ras GTPase-activating protein, conserved site Rho GTPase activation protein Zinc finger, Btk motif
UniProtKB:A2CE77 800
UniProtKB:A0A0R4IE78 806
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rasa4-201 (1) Ensembl 2,403 nt
mRNA rasa4-202 (1) Ensembl 7,508 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations