Gene

tmc2b

ID
ZDB-GENE-060526-262
Name
transmembrane channel-like 2b
Symbol
tmc2b Nomenclature History
Previous Names
  • si:dkey-229d2.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have mechanosensitive ion channel activity. Involved in detection of mechanical stimulus involved in sensory perception of sound; inner ear morphogenesis; and neuromast development. Predicted to localize to integral component of plasma membrane. Is expressed in inner ear; neuromast; and neuromast hair cell. Orthologous to human TMC2 (transmembrane channel like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tmc2b Human Ortholog
No data available
Associated With tmc2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR012496 TMC domain
Family IPR038900 Transmembrane channel-like protein
Domain Details Per Protein
Protein Length TMC domain Transmembrane channel-like protein
UniProtKB:F1QZE9 892
UniProtKB:A0A8M6YZ60 955
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tmc2b-201 (1) Ensembl 2,679 nt
mRNA tmc2b-202 (1) Ensembl 2,359 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations