Gene

tpcn1

ID
ZDB-GENE-060526-199
Name
two pore segment channel 1
Symbol
tpcn1 Nomenclature History
Previous Names
  • si:dkey-125i10.5
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have NAADP-sensitive calcium-release channel activity. Predicted to be involved in ion transport and transmembrane transport. Predicted to localize to endosome membrane and lysosomal membrane. Orthologous to human TPCN1 (two pore segment channel 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Rice et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpcn1 Human Ortholog
No data available
Associated With tpcn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Family IPR028801 Two pore channel protein 1
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain Two pore channel protein 1 Voltage-dependent channel domain superfamily
UniProtKB:A0A8M2BCG3 810
UniProtKB:A0A8N7TFG5 811
UniProtKB:A2BHL7 805
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tpcn1-201 (1) Ensembl 2,373 nt
mRNA tpcn1-202 (1) Ensembl 3,654 nt
mRNA tpcn1-203 (1) Ensembl 2,286 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations