Gene
nlgn3b
- ID
- ZDB-GENE-060526-197
- Name
- neuroligin 3b
- Symbol
- nlgn3b Nomenclature History
- Previous Names
-
- nlgn3a (1)
- si:dkey-125i10.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Is expressed in several structures, including digestive system; gonad; heart; nervous system; and swim bladder. Orthologous to human NLGN3 (neuroligin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism susceptibility, X-linked 1} | 300425 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|
|
UniProtKB:A2BHL9
|
846 | ||||
|
UniProtKB:D0EVX2
|
845 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlgn3b-201
(1)
|
Ensembl | 4,438 nt |
Interactions and Pathways
No data available
Plasmids
No data available