Gene
antxr2a
- ID
- ZDB-GENE-060526-14
- Name
- ANTXR cell adhesion molecule 2a
- Symbol
- antxr2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits Rho GTPase binding activity and actin binding activity. Involved in establishment of mitotic spindle orientation. Localizes to several cellular components, including cleavage furrow; cortical actin cytoskeleton; and midbody. Human ortholog(s) of this gene implicated in fibroma and hyaline fibromatosis syndrome. Is expressed in epiblast. Orthologous to human ANTXR2 (ANTXR cell adhesion molecule 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Castanon et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Castanon et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyaline fibromatosis syndrome | Alliance | Hyaline fibromatosis syndrome | 228600 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002035 | von Willebrand factor, type A |
| Domain | IPR008399 | Anthrax toxin receptor, C-terminal |
| Domain | IPR008400 | Anthrax toxin receptor, extracellular domain |
| Family | IPR017360 | Anthrax toxin receptor |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Anthrax toxin receptor | Anthrax toxin receptor, C-terminal | Anthrax toxin receptor, extracellular domain | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|
|
UniProtKB:A4QP34
|
478 | |||||
|
UniProtKB:A0A8M2BCM1
|
379 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available