Gene
thap1
- ID
- ZDB-GENE-060519-9
- Name
- THAP domain containing, apoptosis associated protein 1
- Symbol
- thap1 Nomenclature History
- Previous Names
-
- zgc:136597
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in torsion dystonia 6. Orthologous to human THAP1 (THAP domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zech et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| torsion dystonia 6 | Alliance | Dystonia 6, torsion | 602629 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | THAP domain-containing protein 1/10 | THAP-type zinc finger | THAP-type zinc finger superfamily |
|---|---|---|---|---|
|
UniProtKB:Q1JPT7
|
225 | |||
|
UniProtKB:A0A0R4IRT9
|
158 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available