Gene
slc6a1a
- ID
- ZDB-GENE-060519-23
- Name
- solute carrier family 6 member 1a
- Symbol
- slc6a1a Nomenclature History
- Previous Names
-
- fj43h03
- wu:fj43h03
- zgc:136569
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable gamma-aminobutyric acid:sodium:chloride symporter activity. Predicted to be involved in amino acid transport and sodium ion transmembrane transport. Predicted to act upstream of or within neurotransmitter transport. Predicted to be located in membrane. Predicted to be active in axon; cell surface; and plasma membrane. Is expressed in central nervous system and eye. Human ortholog(s) of this gene implicated in alcohol dependence and myoclonic-atonic epilepsy. Orthologous to human SLC6A1 (solute carrier family 6 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myoclonic-atonic epilepsy | Alliance | Myoclonic-atonic epilepsy | 616421 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sodium:neurotransmitter symporter | Sodium:neurotransmitter symporter, GABA, GAT-1 | Sodium:neurotransmitter symporter superfamily |
|---|---|---|---|---|
|
UniProtKB:F1QUY7
|
679 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc6a1a-201
(1)
|
Ensembl | 2,429 nt |
Interactions and Pathways
No data available
Plasmids
No data available