Gene
fancc
- ID
- ZDB-GENE-060510-2
- Name
- FA complementation group C
- Symbol
- fancc Nomenclature History
- Previous Names
-
- zgc:154105
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in cellular response to oxidative stress and nucleotide-excision repair. Predicted to localize to Fanconi anaemia nuclear complex. Human ortholog(s) of this gene implicated in Fanconi anemia (multiple); acute myeloid leukemia; breast cancer; pancreatic cancer; and pancytopenia. Is expressed in intermediate cell mass of mesoderm and nervous system. Orthologous to human FANCC (FA complementation group C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group C | Alliance | Fanconi anemia, complementation group C | 227645 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000686 | Fanconi anaemia group C protein |
Domain Details Per Protein
| Protein | Length | Fanconi anaemia group C protein |
|---|---|---|
|
UniProtKB:Q1X872
|
518 | |
|
UniProtKB:B0V1A8
|
518 | |
|
UniProtKB:B0V1A9
|
554 |
Interactions and Pathways
No data available
Plasmids
No data available