Gene

cacna2d2b

ID

ZDB-GENE-060503-99

Name

calcium channel, voltage-dependent, alpha 2/delta subunit 2b

Symbol

cacna2d2b Nomenclature History

Previous Names

si:ch211-11p18.4

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable voltage-gated calcium channel activity. Predicted to act upstream of or within calcium ion transmembrane transport and regulation of monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated calcium channel complex. Orthologous to human CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cacna2d2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cerebellar atrophy with seizures and variable developmental delay	618501

Associated With cacna2d2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002035	von Willebrand factor, type A
Domain	IPR013608	VWA N-terminal
Domain	IPR013680	Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region
Family	IPR051173	Voltage-dependent calcium channel subunit alpha-2/delta
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily