Gene
rims2b
- ID
- ZDB-GENE-060503-893
- Name
- regulating synaptic membrane exocytosis 2b
- Symbol
- rims2b Nomenclature History
- Previous Names
-
- si:ch211-95i5.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane transporter binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; modulation of chemical synaptic transmission; and regulation of membrane potential. Predicted to act upstream of or within exocytosis and regulation of exocytosis. Predicted to be located in membrane and presynaptic active zone. Predicted to be active in cytoskeleton of presynaptic active zone and presynaptic membrane. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cone-rod synaptic disorder syndrome, congenital nonprogressive | 618970 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR010911 | Rab-binding domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR054386 | RIM, zinc finger |
| Family | IPR039032 | Rim-like |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | PDZ domain | PDZ superfamily | Rab-binding domain | Rim-like | RIM, zinc finger | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PSB0
|
1846 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rims2b-201
(1)
|
Ensembl | 3,164 nt | ||
| mRNA |
rims2b-203
(1)
|
Ensembl | 679 nt | ||
| mRNA |
rims2b-204
(1)
|
Ensembl | 482 nt | ||
| ncRNA |
rims2b-005
(1)
|
Ensembl | 468 nt |
Interactions and Pathways
No data available
Plasmids
No data available