Gene

eya3

ID
ZDB-GENE-060503-864
Name
EYA transcriptional coactivator and phosphatase 3
Symbol
eya3 Nomenclature History
Previous Names
  • si:ch211-195b13.2
  • zgc:152966
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in several processes, including histone dephosphorylation; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; and positive regulation of DNA repair. Predicted to localize to nucleus. Is expressed in brain; head; immature eye; and olfactory placode. Orthologous to human EYA3 (EYA transcriptional coactivator and phosphatase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tingaud-Sequeira et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eya3 Human Ortholog
No data available
Associated With eya3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006545 EYA domain
Domain IPR042577 EYA domain, metazoan
Family IPR028472 Eyes absent family
Homologous_superfamily IPR038102 EYA domain superfamily
Domain Details Per Protein
Protein Length EYA domain EYA domain, metazoan EYA domain superfamily Eyes absent family
UniProtKB:A0A8M2BHD8 456
UniProtKB:A0A8M2BHD9 608
UniProtKB:A0JME1 609
UniProtKB:A0A8M2BHG2 608
UniProtKB:A0A8M2BHU7 565
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA eya3-201 (1) Ensembl 4,866 nt
mRNA eya3-202 (1) Ensembl 3,304 nt
mRNA eya3-203 (1) Ensembl 3,257 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations