Gene
edn2
- ID
- ZDB-GENE-060503-774
- Name
- endothelin 2
- Symbol
- edn2 Nomenclature History
- Previous Names
-
- si:ch211-202b2.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable endothelin B receptor binding activity and hormone activity. Predicted to be involved in several processes, including positive regulation of prostaglandin-endoperoxide synthase activity; regulation of systemic arterial blood pressure by endothelin; and vein smooth muscle contraction. Predicted to act upstream of or within regulation of vasoconstriction and vasoconstriction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Goldman et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin | Endothelin-like toxin | Endothelin-like toxin, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q1MT02
|
164 |
Interactions and Pathways
No data available
Plasmids
No data available