Gene
lipea
- ID
- ZDB-GENE-060503-734
- Name
- lipase, hormone-sensitive a
- Symbol
- lipea Nomenclature History
- Previous Names
-
- hsl (1)
- si:dkey-3n22.7
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have lipase activity. Predicted to be involved in cholesterol metabolic process and lipid catabolic process. Human ortholog(s) of this gene implicated in arteriosclerosis; familial partial lipodystrophy type 6; and hypertension. Is expressed in male organism. Orthologous to human LIPE (lipase E, hormone sensitive type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial partial lipodystrophy type 6 | Alliance | Lipodystrophy, familial partial, type 6 | 615980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Alpha/beta hydrolase fold-3 | Hormone-sensitive lipase, N-terminal | Lipase, GDXG, putative histidine active site |
|---|---|---|---|---|---|
|
UniProtKB:A3KPJ7
|
696 |
Interactions and Pathways
No data available
Plasmids
No data available