Gene
gatad2b
- ID
- ZDB-GENE-060503-655
- Name
- GATA zinc finger domain containing 2B
- Symbol
- gatad2b Nomenclature History
- Previous Names
-
- si:dkeyp-66g8.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have sequence-specific DNA binding activity and zinc ion binding activity. Involved in negative regulation of smoothened signaling pathway. Predicted to localize to NuRD complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 18. Orthologous to human GATAD2B (GATA zinc finger domain containing 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lin et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| GAND syndrome | Alliance | GAND syndrome | 615074 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Transcriptional repressor p66 | Transcriptional repressor p66, coiled-coil MBD2-interaction domain | Zinc finger, GATA-type |
|---|---|---|---|---|
|
UniProtKB:A0A8M1N9R4
|
645 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gatad2b-201
(1)
|
Ensembl | 2,635 nt |
Interactions and Pathways
No data available
Plasmids
No data available