Gene
neu1
- ID
- ZDB-GENE-060503-592
- Name
- neuraminidase 1
- Symbol
- neu1 Nomenclature History
- Previous Names
-
- si:ch211-222e23.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Enables alpha-sialidase activity. Involved in regulation of bone remodeling and regulation of skeletal muscle fiber development. Predicted to be located in lysosomal lumen and lysosomal membrane. Predicted to be active in lysosome and membrane. Is expressed in several structures, including gill; heart; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in mucolipidosis. Orthologous to human NEU1 (neuraminidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycoproteinosis | Alliance | Sialidosis, type I | 256550 |
| glycoproteinosis | Alliance | Sialidosis, type II | 256550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sialidase | Sialidase family | Sialidase superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3ASJ5 | InterPro | 314 | |||
| UniProtKB:Q1LWP9 | InterPro | 383 |
Interactions and Pathways
No data available
Plasmids
No data available