Gene
ipo8
- ID
- ZDB-GENE-060503-3
- Name
- importin 8
- Symbol
- ipo8 Nomenclature History
- Previous Names
-
- si:ch211-116i17.1
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have Ran GTPase binding activity. Predicted to be involved in protein import into nucleus. Predicted to localize to cytosol and nuclear envelope. Orthologous to human IPO8 (importin 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Mbarek et al., 2023
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| VISS syndrome | 619472 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Exportin-2, central domain | Importin-beta, N-terminal domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUE9
|
992 | ||||
|
UniProtKB:A0A8M3B1K0
|
658 | ||||
|
UniProtKB:A0A8M3ARG6
|
661 | ||||
|
UniProtKB:A0A2R8RMT5
|
1018 | ||||
|
UniProtKB:B7ZV68
|
1015 |
Interactions and Pathways
No data available
Plasmids
No data available