Gene
jarid2b
- ID
- ZDB-GENE-060503-246
- Name
- jumonji and AT-rich interaction domain containing 2b
- Symbol
- jarid2b Nomenclature History
- Previous Names
-
- si:dkey-211c3.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have chromatin binding activity and histone demethylase activity. Predicted to be involved in several processes, including chromatin remodeling; negative regulation of transcription, DNA-templated; and regulation of histone methylation. Predicted to colocalize with ESC/E(Z) complex. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Developmental delay with variable intellectual disability and dysmorphic facies | 620098 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ARID DNA-binding domain | ARID DNA-binding domain superfamily | JmjC domain | JmjN domain | Zinc finger, C5HC2-type |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AKY8
|
1303 | |||||
|
UniProtKB:Q1LVC2
|
1319 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
jarid2b-201
(1)
|
Ensembl | 4,421 nt | ||
| mRNA |
jarid2b-202
(1)
|
Ensembl | 3,915 nt |
Interactions and Pathways
No data available
Plasmids
No data available