Gene

dock11

ID
ZDB-GENE-060503-196
Name
dedicator of cytokinesis 11
Symbol
dock11 Nomenclature History
Previous Names
  • si:ch211-150g2.3
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human DOCK11 (dedicator of cytokinesis 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dock11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Autoinflammatory disease, multisystem, with immune dysregulation, X-linked 301109
Associated With dock11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR021816 Dedicator of cytokinesis C/D, N-terminal
Domain IPR027007 C2 DOCK-type domain
Domain IPR027357 DOCKER domain
Domain IPR037809 Dedicator of cytokinesis D, C2 domain
Domain IPR046769 DOCKER, Lobe A
Domain IPR046770 DOCKER, Lobe B
Domain IPR046773 DOCKER, Lobe C
Family IPR026791 Dedicator of cytokinesis
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR043161 Dedicator of cytokinesis, C-terminal, lobe A
Homologous_superfamily IPR043162 Dedicator of cytokinesis, C-terminal, lobe C
Domain Details Per Protein
Protein Length C2 DOCK-type domain C2 domain superfamily Dedicator of cytokinesis Dedicator of cytokinesis C/D, N-terminal Dedicator of cytokinesis, C-terminal, lobe A Dedicator of cytokinesis, C-terminal, lobe C Dedicator of cytokinesis D, C2 domain DOCKER domain DOCKER, Lobe A DOCKER, Lobe B DOCKER, Lobe C PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A8M9Q1V0 2041
UniProtKB:B0R034 2067
UniProtKB:A0A0R4ILW7 2057
UniProtKB:A0A8M9PP60 2054
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dock11-201 (1) Ensembl 6,209 nt
mRNA dock11-202 (1) Ensembl 9,964 nt
mRNA dock11-203 (1) Ensembl 9,806 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations