Gene
hcn3
- ID
- ZDB-GENE-060503-193
- Name
- hyperpolarization activated cyclic nucleotide-gated potassium channel 3
- Symbol
- hcn3 Nomenclature History
- Previous Names
-
- si:ch211-130o18.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport; regulation of membrane depolarization; and sodium ion transmembrane transport. Predicted to act upstream of or within potassium ion transport; sodium ion transport; and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of HCN channel complex. Predicted to be active in axon and dendrite. Orthologous to human HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR013621 | Ion transport N-terminal |
| Family | IPR051413 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Ion transport domain | Ion transport N-terminal | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F6NQL8
|
639 |
Interactions and Pathways
No data available
Plasmids
No data available