Gene

cdkn3

ID

ZDB-GENE-060427-2

Name

cyclin dependent kinase inhibitor 3

Symbol

cdkn3 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in cell cycle arrest and cilium assembly. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is expressed in myotome and somite. Orthologous to human CDKN3 (cyclin dependent kinase inhibitor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158182 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdkn3 Human Ortholog

No data available

Associated With cdkn3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR022778	CDKN3 domain
Family	IPR008425	Cyclin-dependent kinase inhibitor 3
Family	IPR050561	Protein Tyrosine Phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like