Gene
avil
- ID
- ZDB-GENE-060421-6683
- Name
- advillin
- Symbol
- avil Nomenclature History
- Previous Names
-
- zgc:136857
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in cytoskeleton organization. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human AVIL (advillin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrotic syndrome type 21 | Alliance | Nephrotic syndrome, type 21 | 618594 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003128 | Villin headpiece |
| Domain | IPR007123 | Gelsolin-like domain |
| Family | IPR007122 | Villin/Gelsolin |
| Homologous_superfamily | IPR029006 | ADF-H/Gelsolin-like domain superfamily |
| Homologous_superfamily | IPR036180 | Gelsolin-like domain superfamily |
| Homologous_superfamily | IPR036886 | Villin headpiece domain superfamily |
Domain Details Per Protein
| Protein | Length | ADF-H/Gelsolin-like domain superfamily | Gelsolin-like domain | Gelsolin-like domain superfamily | Villin/Gelsolin | Villin headpiece | Villin headpiece domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1RLT7
|
811 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available