Gene

ing1

ID

ZDB-GENE-060421-4388

Name

inhibitor of growth family, member 1

Symbol

ing1 Nomenclature History

Previous Names

zgc:136918

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have methylated histone binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and squamous cell carcinoma. Orthologous to human ING1 (inhibitor of growth family member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ing1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
head and neck squamous cell carcinoma	Alliance	Squamous cell carcinoma, head and neck, somatic	275355

Associated With ing1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR024610	Inhibitor of growth protein, N-terminal histone-binding
Domain	IPR028643	Inhibitor of growth protein 1, PHD-type zinc finger
Family	IPR028651	ING family
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type